La final se jugará en el Puskás Aréna de Budapest.
El torneo se disputó desde agosto de 2022 hasta mayo de 2023 y la final se jugó en el Puskás Aréna de Budapest, Hungría. El campeón jugará la Supercopa de Europa 2023 contra el campeón de la Liga de Campeones de la UEFA 2022-23, además se clasificará para la fase de grupos de la Liga de Campeones de la UEFA 2023-24.
Partidos
| Semifinales | Jueves 11/5 | Jueves 18, 16.00 | |
  Juventus | 1-1 | 1-2 |   Sevilla |
 Roma | 1-0 | 0-0 |   B. Leverkusen |
| Cuartos de final | Ida Jueves 13 | Vuelta Jueves 20 | |
| Juventus | 1-0 | 1-1 |   Sporting Lisboa |
  Manchester United | 2-2 | 0-3 | Sevilla |
  Feyenoord | 1-0 | 1-4 | Roma |
| B. Leverkusen | 1-1 | 1-4 |  Union SG |
| Octavos de final | Ida Jueves 9/3 | Vuelta Jueves 16/3- 17.00 | |
| Roma | 2-0 | 0-0 |  Real Sociedad |
 Union Berlin | 3-3 | 0-3 |  Union SG |
| Juventus | 1-0 | 2-0 |  Friburgo |
| B. Leverkusen | 2-0 | 2-0 |   Ferencvarosi |
| Sporting Lisboa | 2-2 | 1-1 (5-3) |  Arsenal FC |
| Sevilla | 2-0 | 0-1 |   Fenerbahce |
  Shakhtar | 1-1 | 1-7 | Feyenoord |
| Manchester United | 4-1 | 1-0 |  Betis |
| 16vos de final | Ida Jueves 16/2 | Vuelta Jueves 23/2 | |
 Barcelona | 2-2 | 1-2 | Manchester United |
 Ajax | 0-0 | 1-3 | Union Berlin |
| Juventus | 1-1 | 3-0 |   Nantes |
| B. Leverkusen | 2-3 | 3-2 (5-3) |  Mónaco |
| Sporting Lisboa | 1-1 | 0-4 |   Midtjylland |
| Sevilla | 3-0 | 0-2 |  PSV |
| Shakhtar | 2-1 | 1-2 (3-2) |  Rennes |
  Salzburgo | 1-0 | 0-2 | Roma |
Posiciones
GRUPO A
| # | Equipo | Pts | PJ | PG | PE | PP | GF | GC | DIF |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Arsenal FC | 15 | 6 | 5 | 0 | 1 | 8 | 3 | +5 |
| 2 | PSV | 13 | 6 | 4 | 1 | 1 | 15 | 4 | +11 |
| 3 |   BodoGlimt | 4 | 6 | 1 | 1 | 4 | 5 | 10 | -5 |
| 4 |   Zurich | 3 | 6 | 1 | 0 | 5 | 5 | 16 | -11 |
GRUPO B
| # | Equipo | Pts | PJ | PG | PE | PP | GF | GC | DIF |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Fenerbahce | 14 | 6 | 4 | 2 | 0 | 13 | 7 | +6 |
| 2 | Rennes | 12 | 6 | 3 | 3 | 0 | 11 | 8 | +3 |
| 3 |   AEK Larnaca | 5 | 6 | 1 | 2 | 3 | 7 | 10 | -3 |
| 4 |  Dinamo Kiev | 1 | 6 | 0 | 1 | 5 | 5 | 11 | -6 |
GRUPO C
| # | Equipo | Pts | PJ | PG | PE | PP | GF | GC | DIF |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Betis | 16 | 6 | 5 | 1 | 0 | 12 | 4 | +8 |
| 2 | Roma | 10 | 6 | 3 | 1 | 2 | 11 | 7 | +4 |
| 3 |   Ludogorets | 7 | 6 | 2 | 1 | 3 | 8 | 9 | -1 |
| 4 |   HJK | 1 | 6 | 0 | 1 | 5 | 2 | 13 | -11 |
GRUPO D
| # | Equipo | Pts | PJ | PG | PE | PP | GF | GC | DIF |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Union SG | 13 | 6 | 4 | 1 | 1 | 11 | 7 | +4 |
| 2 | Union Berlin | 12 | 6 | 4 | 0 | 2 | 4 | 2 | +2 |
| 3 |  Braga | 10 | 6 | 3 | 1 | 2 | 9 | 7 | +2 |
| 4 |   Malmo | 0 | 6 | 0 | 0 | 6 | 3 | 11 | -8 |
GRUPO E
| # | Equipo | Pts | PJ | PG | PE | PP | GF | GC | DIF |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Real Sociedad | 15 | 6 | 5 | 0 | 1 | 10 | 2 | +8 |
| 2 | Manchester United | 15 | 6 | 5 | 0 | 1 | 10 | 3 | +7 |
| 3 |   FC Sheriff | 6 | 6 | 2 | 0 | 4 | 4 | 10 | -6 |
| 4 |  Omonia Nicosia | 0 | 6 | 0 | 0 | 6 | 3 | 12 | -9 |
GRUPO F
| # | Equipo | Pts | PJ | PG | PE | PP | GF | GC | DIF |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Feyenoord | 8 | 6 | 2 | 2 | 2 | 13 | 9 | +4 |
| 2 | Midtjylland | 8 | 6 | 2 | 2 | 2 | 12 | 8 | +4 |
| 3 |  Lazio | 8 | 6 | 2 | 2 | 2 | 9 | 11 | -2 |
| 4 |  Sturm Graz | 8 | 6 | 2 | 2 | 2 | 4 | 10 | -6 |
GRUPO G
| # | Equipo | Pts | PJ | PG | PE | PP | GF | GC | DIF |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Friburgo | 14 | 6 | 4 | 2 | 0 | 13 | 3 | +10 |
| 2 | Nantes | 9 | 6 | 3 | 0 | 3 | 6 | 11 | -5 |
| 3 |   Qarabag | 8 | 6 | 2 | 2 | 2 | 9 | 5 | +4 |
| 4 |   Olympiakos | 2 | 6 | 0 | 2 | 4 | 2 | 11 | -9 |
GRUPO H
| # | Equipo | Pts | PJ | PG | PE | PP | GF | GC | DIF |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Ferencvarosi | 10 | 6 | 3 | 1 | 2 | 8 | 9 | -1 |
| 2 | Mónaco | 10 | 6 | 3 | 1 | 2 | 9 | 8 | +1 |
| 3 |  Trabzonspor | 9 | 6 | 3 | 0 | 3 | 11 | 9 | +2 |
| 4 |   Estrella Roja | 6 | 6 | 2 | 0 | 4 | 9 | 11 | -2 |
Jugados
| Jornada 6 | Jueves 3 | |
| Midtjylland | 2-0 | Sturm Graz |
| Qarabag | 1-1 | Friburgo |
| Feyenoord | 1-0 | Lazio |
| Mónaco | 4-1 | Estrella Roja |
| Olympiakos | 0-2 | Nantes |
| Real Sociedad | 0-1 | Manchester United |
| FC Sheriff | 1-0 | Omonia Nicosia |
| Trabzonspor | 1-0 | Ferencvarosi |
| Arsenal FC | 1-0 | Zurich |
| BodoGlimt | 1-2 | PSV |
| Dinamo Kiev | 0-2 | Fenerbahce |
| Betis | 3-0 | HJK |
| Rennes | 1-1 | AEK Larnaca |
| Roma | 3-1 | Ludogorets |
| Braga | 2-1 | Malmo |
| Union SG | 0-1 | Union Berlin |
| Fecha 5 | Jueves 27 | |
| Union Berlin | 1-0 | Braga |
| AEK Larnaca | 3-3 | Dinamo Kiev |
| Fenerbahce | 3-3 | Rennes |
| Lazio | 2-1 | Midtjylland |
| Ludogorets | 0-1 | Betis |
| Malmo | 0-2 | Union SG |
| PSV | 2-0 | Arsenal FC |
| Zurich | 2-1 | BodoGlimt |
| Estrella Roja | 2-1 | Trabzonspor |
| Ferencvarosi | 1-1 | Mónaco |
| HJK | 1-2 | Roma |
| Manchester United | 3-0 | FC Sheriff |
| Nantes | 2-1 | Qarabag |
| Omonia Nicosia | 0-2 | Real Sociedad |
| Friburgo | 1-1 | Olympiakos |
| Sturm Graz | 1-0 | Feyenoord |
| Fecha 4 | Jueves 13 | |
| AEK Larnaca | 1-2 | Fenerbahce |
| BodoGlimt | 0-1 | Arsenal FC |
| Dinamo Kiev | 0-1 | Rennes |
| Qarabag | 0-0 | Olympiakos |
| Feyenoord | 2-2 | Midtjylland |
| Nantes | 0-4 | Friburgo |
| Betis | 1-1 | Roma |
| Union SG | 3-3 | Braga |
| Union Berlin | 1-0 | Malmo |
| Ferencvarosi | 2-1 | Estrella Roja |
| Lazio | 2-2 | Sturm Graz |
| Ludogorets | 2-0 | HJK |
| Manchester United | 1-0 | Omonia Nicosia |
| PSV | 5-0 | Zurich |
| Real Sociedad | 3-0 | FC Sheriff |
| Trabzonspor | 4-0 | Mónaco |
| Fecha 3 | Jueves 6 de octubre | |
| Estrella Roja | 4-1 | Ferencvarosi |
| HJK | 1-1 | Ludogorets |
| Malmo | 0-1 | Union Berlin |
| Mónaco | 3-1 | Trabzonspor |
| Omonia Nicosia | 2-3 | Manchester United |
| Sturm Graz | 0-0 | Lazio |
| FC Sheriff | 0-2 | Real Sociedad |
| Zurich | 1-5 | PSV |
| Arsenal FC | 3-0 | BodoGlimt |
| Midtjylland | 2-2 | Feyenoord |
| Fenerbahce | 2-0 | AEK Larnaca |
| Olympiakos | 0-3 | Qarabag |
| Rennes | 2-1 | Dinamo Kiev |
| Roma | 1-2 | Betis |
| Friburgo | 2-0 | Nantes |
| Braga | 1-2 | Union SG |
| Fecha 2 | Jueves 15 | |
| Midtjylland | 5-1 | Lazio |
| Qarabag | 3-0 | Nantes |
| Feyenoord | 6-0 | Sturm Graz |
| Mónaco | 0-1 | Ferencvarosi |
| Olympiakos | 0-3 | Friburgo |
| Real Sociedad | 2-1 | Omonia Nicosia |
| FC Sheriff | 0-2 | Manchester United |
| Trabzonspor | 2-1 | Estrella Roja |
| BodoGlimt | 2-1 | Zurich |
| Dinamo Kiev | 0-1 | AEK Larnaca |
| Betis | 3-2 | Ludogorets |
| Rennes | 2-2 | Fenerbahce |
| Roma | 3-0 | HJK |
| Braga | 1-0 | Union Berlin |
| Union SG | 3-2 | Malmo |
| Arsenal FC | 1-0 (jugado 20/10) | PSV |
| Fecha 1 | Jueves 8 de septiembre | ||
| 13:45 | Union Berlin | 0-1 | Union SG |
| 13:45 | AEK Larnaca | 1-2 | Rennes |
| 13:45 | Fenerbahce | 2-1 | Dinamo Kiev |
| 13:45 | HJK | 0-2 | Betis |
| 13:45 | Ludogorets | 2-1 | Roma |
| 13:45 | Malmo | 0-2 | Braga |
| 13:45 | PSV | 1-1 | BodoGlimt |
| 13:45 | Zurich | 1-2 | Arsenal FC |
| 16:00 | Estrella Roja | 0-1 | Mónaco |
| 16:00 | Ferencvarosi | 3-2 | Trabzonspor |
| 16:00 | Lazio | 4-2 | Feyenoord |
| 16:00 | Manchester United | 0-1 | Real Sociedad |
| 16:00 | Nantes | 2-1 | Olympiakos |
| 16:00 | Omonia Nicosia | 0-3 | FC Sheriff |
| 16:00 | Friburgo | 2-1 | Qarabag |
| 16:00 | Sturm Graz | 1-0 | Midtjylland |
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